- 产品详情
- 产品参数
订购信息
| 货号 | 种属 | 载体 | 描述 | 价格 | 周期 |
| YHO10025 | Human ORF | pDoubleEx-EGFP | Homo sapiens vascular endothelial growth factor A (VEGFA),transcript variant 1, mRNA NM_001025366 | 4000 | 3-4 周 |
基本信息
| 基因名称： | VEGFA |
| NCBI序列号： | NM_001025366 |
| 基因描述： | Homo sapiens vascular endothelial growth factor A (VEGFA),transcript variant 1, mRNA NM_001025366 |
| 基因种属： | Human |
产品说明书
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载体信息
基因简介
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
