订购信息
货号 | 种属 | 载体 | 描述 | 荧光 | 价格 | 周期 |
rAd004364 | Human | 腺病毒 | Homo sapiens CCAAT/enhancer binding protein alpha (CEBPA),transcript variant 1, mRNANM_004364 | 带绿色荧光 | 9000 | 7-8 周 |
基本信息
基因名称: | CEBPA |
NCBI序列号: | NM_004364 |
基因描述: | Homo sapiens CCAAT/enhancer binding protein alpha (CEBPA),transcript variant 1, mRNA NM_004364 |
基因种属: | Human |
荧光标记: | 带绿色荧光 |
腺病毒滴度: | 109~1010pfu/ml |
产品说明书
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基因简介
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.