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人 CEBPA (NM_004364) ORF克隆产品信息
订购信息
| 货号 | 种属 | 载体 | 描述 | 价格 | 周期 |
| HO100070 | Human ORF | pDoubleEx-EGFP | Homo sapiens CCAAT/enhancer binding protein alpha (CEBPA),transcript variant 1, mRNA NM_004364 | 4000 | 3-4 周 |
基本信息
| 基因名称： | CEBPA |
| 基因别名： | C/EBP-alpha; CEBP; CEBP; CCAAT/enhancer binding protein alpha; CCAAT/enhancer binding protein (C/EBP), alpha |
| NCBI序列号： | NM_004364 |
| 基因描述： | Homo sapiens CCAAT/enhancer binding protein alpha (CEBPA),transcript variant 1, mRNA NM_004364 |
| 基因种属： | Human |
产品说明书
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载体信息
基因简介
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
