- 产品详情
- 产品参数
小鼠 TGFB1 (NM_011577) ORF克隆产品信息
订购信息
| 货号 | 种属 | 载体 | 描述 | 价格 | 周期 |
| YMO11791 | Mouse ORF | pLVX-IRES-Puro | Mus musculus transforming growth factor, beta 1 (Tgfb1), mRNANM_011577 | 3000 | 1 周 |
基本信息
| 基因名称： | TGFB1 |
| NCBI序列号： | NM_011577 |
| 基因描述： | Mus musculus transforming growth factor, beta 1 (Tgfb1), mRNA NM_011577 |
| 基因种属： | Mouse |
产品说明书
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载体信息
基因简介
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
