- 产品详情
- 产品参数
人 ANPEP (NM_001150) ORF克隆产品信息
订购信息
| 货号 | 种属 | 载体 | 描述 | 价格 | 周期 |
| HO001150 | Human ORF | pcDNA3.1-Hygro(+) | Homo sapiens alanyl (membrane) aminopeptidase (Anpep，Apn，Cd13，Lap-1，Lap1，P150), mRNA. NM_001150 | 5000 4500 | 1 周 |
基本信息
| 基因名称： | ANPEP |
| NCBI序列号： | NM_001150 |
| 基因描述： | Homo sapiens alanyl (membrane) aminopeptidase (Anpep，Apn，Cd13，Lap-1，Lap1，P150), mRNA. NM_001150 |
| 基因种属： | Human |
产品说明书
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基因简介
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
