订购信息
货号 | 种属 | 载体 | 描述 | 荧光 | 价格 | 周期 |
rAd170665 | Human | 腺病毒 | Homo sapiens ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (ATP2A2), transcript variant b, mRNA NM_170665 | 无荧光 | 11000 | 7-8 周 |
基本信息
基因名称: | ATP2A2 |
NCBI序列号: | NM_170665 |
基因描述: | Homo sapiens ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (ATP2A2), transcript variant b, mRNA NM_170665 |
基因种属: | Human |
荧光标记: | 无荧光 |
腺病毒滴度: | 109~1010pfu/ml |
产品说明书
请联系YRgene技术支持索取产品说明书。
基因简介
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.